• Users Online: 44
  • Print this page
  • Email this page
COMMENTARY
Year : 2013  |  Volume : 7  |  Issue : 3  |  Page : 109-111

Combining kidney paired donation with desensitization increases renal transplantation rate in highly sensitized patients


1 Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr. HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Ahmedabad 380016, Gujarat, India
2 Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology, Institute of Kidney Diseases and Research Center, Dr. HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Ahmedabad, 380016, Gujarat, India

Correspondence Address:
Vivek B Kute
Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr. HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Ahmedabad 380016, Gujarat
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.1016/j.ijt.2013.05.002

Get Permissions

When a desensitization protocol is unsuccessful, a look-back into kidney paired donation (KPD) pool may facilitate transplantation. A 53-year male developed end stage renal disease (ESRD) due to chronic glomerulonephritis. His immunological profile remained unacceptable for transplantation with wife as potential donor even after desensitization protocol. Lymphocytotoxicity crossmatch, flow crossmatch and donor specific antibodies [DSA] were favorable for transplantation with rescue swap donor. Two-way KPD exchange was performed with steroid and rabbit anti-thymoglobulin induction under triple immunosuppressive regimen. Both recipients were discharged with stable allograft function. This case suggests that in case of an unsuccessful attempt at desensitization, rescue KPD can be used for salvaging failed desensitization treatment and increase the transplantation rate.


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed90    
    Printed11    
    Emailed0    
    PDF Downloaded29    
    Comments [Add]    
    Cited by others 2    

Recommend this journal