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CASE REPORT
Year : 2014  |  Volume : 8  |  Issue : 1  |  Page : 22-24

Successful eradication of cryptosporidium in kidney transplant recipients – Two case reports


1 Assistant Professor, Department of Nephrology, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry 605006, India
2 Associate Professor, Department of Nephrology, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry 605006, India
3 Senior Resident, Department of Nephrology, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry 605006, India

Correspondence Address:
P S Priyamvada
Assistant Professor, Department of Nephrology, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry 605006
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.1016/j.ijt.2014.01.013

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Cryptosporidium infection can present as refractory diarrhoea in solid organ transplant recipients. Many drugs have been shown in vitro activity against cryptosporidium. Optimum therapy to treat a clinical infection with cryptosporidium is not known. It is often difficult to achieve parasitological cure and this may require reduction of immunosuppressive drugs coupled with antiparasitic agents. Nitazoxanide is a thiazolide antiparasitic which is currently approved for treatment of cryptosporidiosis in immunocompetent persons aged above one year. There are no guidelines for the treatment of cryptosporidiosis in solid organ transplant recipients. We report our experience of extended treatment with Nitazoxanide and Azithromycin for two post renal transplant patients with cryptosporidium diarrhoea which resulted in clinical as well as parasitological cure.


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