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Year : 2014  |  Volume : 8  |  Issue : 1  |  Page : 18-21

Isolated cerebellar pheohyphomycosis in a patient with combined hepatic and renal transplantation

1 Department of Pathology, Sir Ganga Ram Hospital, New Delhi 110060, India
2 Department of Liver Transplantation, Sir Ganga Ram Hospital, New Delhi 110060, India

Correspondence Address:
Gupta Pallav
Department of Pathology, Sir Ganga Ram Hospital, New Delhi 110060
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Source of Support: None, Conflict of Interest: None

DOI: 10.1016/j.ijt.2014.01.015

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Introduction: Pheohyphomycosis is a pigmented fungus which can present as an isolated brain abscess in both immunocompetent and immunocompromised individuals with almost similar mortality in the two groups. In brain, cerebrum is the usual site of involvement. Case report: We present a case of isolated cerebellar pheohyphomycosis in 48-year-old male diagnosed on histopathological examination. Patient was on immunosuppressive medication as he had received combined hepatic and renal transplantation. Discussion: Isolated cerebellar involvement is extremely uncommon in pheohyphomycosis. These fungi have melanin pigment present in their walls which helps them in evading host defence. Tissue for performing fungal culture may not be always available in brain infections as biopsy tissue is not routinely sent for culture in unsuspected cases. In these patients histopathological examination with special can serve as a useful in identification of fungal species and can be life saving for the patient.

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