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CASE REPORT
Year : 2016  |  Volume : 10  |  Issue : 1  |  Page : 30-32

A de novo Randall disease in a kidney transplant recipient: A case report


Department of Nephrology, Dialysis and Renal Transplantation, Ibn Rochd University Hospital of Casablanca, 1, Quartier des Hôpitaux, Casablanca 20100, Morocco

Correspondence Address:
Béfa Noto-Kadou-Kaza
Department of Nephrology, Dialysis and Renal Transplantation, Ibn Rochd University Hospital of Casablanca, 1, Quartier des Hôpitaux, Casablanca 20100
Morocco
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Source of Support: None, Conflict of Interest: None


DOI: 10.1016/j.ijt.2016.03.002

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Introduction: Randall disease called “monoclonal immunoglobulin deposition disease (MIDD)” and is defined histologically by the presence of deposits immunoglobulin (Ig) monoclonal, diffuse and continuous linear, non-organized within the tubular basement membranes, and frequently glomerular basement and vascular, often associated with accumulation of extracellular matrix. Only 11 cases of de novo Randall disease post-renal transplantation have been reported in the literature. Case presentation: We report a case of de novo Randall kidney and liver disease associated with myeloma diagnosed in the 20th month post-renal transplant in a woman of 49 years. The treatment had consisted of a decrease of immunosuppression and put on chemotherapy. The evolution was marked by graft loss with return to dialysis. The death occurred in a context of septic shock after the first cure of chemotherapy. Conclusion: A de novo Randall disease post-renal transplantation is not only very rare, but also there is no consensus of it is a management.


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