| CASE REPORT |
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| Year : 2016 | Volume
: 10
| Issue : 1 | Page : 30-32 |
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A de novo Randall disease in a kidney transplant recipient: A case report
Amina Izem, Béfa Noto-Kadou-Kaza, Kawtar Mabrouk, Naoufal Mtiou, Kossi Akomola Sabi, Selma El Khayat, Mohamed Zamd, Ghislaine Medkouri, Mohamed Gharbi Bengahanem, Benyounes Ramdani
Department of Nephrology, Dialysis and Renal Transplantation, Ibn Rochd University Hospital of Casablanca, 1, Quartier des Hôpitaux, Casablanca 20100, Morocco
Correspondence Address:
Béfa Noto-Kadou-Kaza
Department of Nephrology, Dialysis and Renal Transplantation, Ibn Rochd University Hospital of Casablanca, 1, Quartier des Hôpitaux, Casablanca 20100
Morocco
 Source of Support: None, Conflict of Interest: None
DOI: 10.1016/j.ijt.2016.03.002
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Introduction: Randall disease called “monoclonal immunoglobulin deposition disease (MIDD)” and is defined histologically by the presence of deposits immunoglobulin (Ig) monoclonal, diffuse and continuous linear, non-organized within the tubular basement membranes, and frequently glomerular basement and vascular, often associated with accumulation of extracellular matrix. Only 11 cases of de novo Randall disease post-renal transplantation have been reported in the literature.
Case presentation: We report a case of de novo Randall kidney and liver disease associated with myeloma diagnosed in the 20th month post-renal transplant in a woman of 49 years. The treatment had consisted of a decrease of immunosuppression and put on chemotherapy. The evolution was marked by graft loss with return to dialysis. The death occurred in a context of septic shock after the first cure of chemotherapy.
Conclusion: A de novo Randall disease post-renal transplantation is not only very rare, but also there is no consensus of it is a management.
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