Indian Journal of Transplantation

ORIGINAL ARTICLE
Year
: 2019  |  Volume : 13  |  Issue : 1  |  Page : 20--24

Spectrum of asymptomatic bacteriuria in renal allograft recipients and its short-term effect on graft outcome: Experience of a Tertiary Care Center from Northwest India


Gaurav Shekhar Sharma, Dhananjay Agarwal, Vinay Rathore, Alok Kumar Pandey, Rajesh Jhorawat, Sanjeev Kumar Sharma, Pankaj Beniwal, Vinay Malhotra 
 Department of Nephrology, SMS Medical College and Hospital, Jaipur, Rajasthan, India

Correspondence Address:
Dr. Rajesh Jhorawat
Department of Nephrology, SMS Medical College and Hospital, Jaipur, Rajasthan
India

Introduction: Asymptomatic bacteriuria (AB) is not uncommon after renal transplantation with limited data from developing countries; we did this study to assess the microbiological spectrum and its short-term graft outcome in our tertiary care center. Materials and Methods: It is a prospective observational study. We included all the patients who underwent renal transplantation over a period of 18 months, from January 2016 to June 2017. Patients who had indwelling urinary catheter beyond 5 days posttransplant and those with persistent graft dysfunction within 6 months of transplant were excluded from the study. Results: A total of 67 patients were included in the study with a mean age of 33.78 ± 8.91 years and a male-to-female ratio of 7:1; live-related donors were 36 (53.73%), live unrelated were 19 (28.35%), and 12 (17.91%) were cadaveric renal allograft recipients (RARs). Twenty-eight (41.79%) patients had 42 episodes of AB over 6 months of follow-up. The maximum episodes occurred within 1 month of postrenal transplantation, and 42 out of 67 (62.68%) RARs had bacterial growth in their double-J ureteral stents (USs). The most frequently isolated pathogen from urine was Escherichia coli (n = 14, 33.33%), whereas Pseudomonas aeruginosa (n = 10, 23.80%) was in US culture (USC). The prevalence of AB was higher in cadaveric RARs compared to live RARs (83.33% vs. 32.72%, P = 0.001) and with bacterial growth in the USC compared to those who did not show any growth in USs (57.14% vs. 16.0%, P = 0.001). However, the estimated glomerular filtration rate between those with AB and those without at 6 months of follow-up (66.36 ± 14.98 vs. 66.10 ± 13.83 ml/min/1.73 m2, P = 0.943) was not different. Conclusion: AB is not uncommon in RARs and it is more common in cadaveric RARs and those with growth in US culture without compromise in allograft function at 6 months postrenal transplant.


How to cite this article:
Sharma GS, Agarwal D, Rathore V, Pandey AK, Jhorawat R, Sharma SK, Beniwal P, Malhotra V. Spectrum of asymptomatic bacteriuria in renal allograft recipients and its short-term effect on graft outcome: Experience of a Tertiary Care Center from Northwest India.Indian J Transplant 2019;13:20-24


How to cite this URL:
Sharma GS, Agarwal D, Rathore V, Pandey AK, Jhorawat R, Sharma SK, Beniwal P, Malhotra V. Spectrum of asymptomatic bacteriuria in renal allograft recipients and its short-term effect on graft outcome: Experience of a Tertiary Care Center from Northwest India. Indian J Transplant [serial online] 2019 [cited 2022 Nov 27 ];13:20-24
Available from: https://www.ijtonline.in/article.asp?issn=2212-0017;year=2019;volume=13;issue=1;spage=20;epage=24;aulast=Sharma;type=0