Aim/Objective: ABO incompatible kidney transplantations are getting popular all over the world. It is essential that such transplantations are carried out in our country also. Material and methods: Thirteen patients who had undergone ABO incompatible transplantations in a single center since 2009 were studied. The transplantations have been across different blood group combinations. The preconditioning of the patient was done as per the Japanese protocol. Results: The patients were followed up between 4 weeks to 28 months. Two patients had immediate antibody-mediated rejection with loss of graft. The rest 11 patients have normal graft function without any complication. Conclusion: Successful ABO incompatible transplantation is feasible in our country without endangering the life of recipient with reasonable cost control. Further studies are required to modify the protocol to prevent immediate antibody-mediated rejections (ABMR).